Biopharmaceutical CMO & CRO Production Capacity Study—a Deep-dive on Firms Opting for Contract Services

CMOs are exploring the potential of mammalian cell culture production amidst soaring demand for biopharmaceutical contract manufacturing services. Incumbents, such as Charles River and Lonza have furthered investments in mammalian cells. To illustrate, in May 2021, Lonza announced pouring USD 936 million to bolster the footprint of mammalian drug substance manufacturing sites in the U.S. and Switzerland. 

Biopharmaceutical firms are responding to the demand for outsourced services with bullish investments in research activities. For instance, in July 2022, Wuxi Biologics contemplated expanding its large-scale drug product & drug substance manufacturing capabilities and R&D in Singapore.

Adoption of Contract Development & Manufacturing Organization (CDMO) and Contract Manufacturing Organization (CMO) with surging demand for Monoclonal Antibodies (MAbs) products will boost the market share. The final report, along with the database, will peruse the following dynamics:

• Insights on commercial availability and annual approvals of MAb products.

• Commercially available biopharmaceuticals and biologics produced using mammalian cell lines.

• Competitive landscape with industry developments.

• CMO Mapping of 88 companies.

Get your copy or request a free sample of the report “Biopharmaceutical CMO & CRO Production Capacity Study,” compiled and published by Grand View Research. 

Biopharmaceutical CMO & CRO Production Capacity Report Scope

CMO Capacity mapping (for 88 companies)

Key Players: Location Mapping & existing Capacities

Recent expansions/ Future plans

Comparative Heat Map

Get more insights from our in-depth market intelligence report, “Biopharmaceutical CMO And CRO Market Size, Share & Trends Analysis Report By Source (Mammalian, Non-mammalian), By Service (Contract Manufacturing, Contract Research), By Product, And Segment Forecasts, 2023 – 2030.”

About Us

Grand View Research, Inc. is a market research and consulting company that provides off-the-shelf, customized research reports and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and energy. With a deep-seated understanding of varied business environments, Grand View Research provides strategic objective insights.

Find More information @ https://www.grandviewresearch.com/info/trend-reports

Contract Research Organizations—a study on Top 50 CROs in the Healthcare Industry

An uptick in clinical trials and demand for advanced therapy medicinal products (ATMPs) have offered compelling opportunities for contract research organizations (CROs). The U.S. National Library of Medicine notes that around 83,230 clinical trial studies are currently active and/or recruiting globally. Amidst stiff competition and the soaring USD 1.5 trillion industry of medical device and drugs, acquisitions of small-scale innovative players, outsourcing and R&D activities have become noticeable. Outsourcing of clinical trials to CROs is mainly attributed to technical prowess and cost-effectiveness. 

With the huge repository of Grand View Research, the study will offer a bird’s eye view of financial performance, including but not limited to EBIT/EBITA, total revenue, net income, net profit, working capital, income & cash flow and Debt/Equity ratio. The report will offer a deep dive of major service/s rendered by top 50 CROs. The final report, along with the database, will peruse into following dynamics:

• Organization structure and team composition of the listed CROs.
• Stock exchange performance, including earnings per share, P/E ratio and quick ratio.
• Global penetration with the regional level breakdown.
• SWOT analysis, patient recruitment platforms/partners, special recognition/awards by industry, service benchmarking and growth plans.

Get your copy or request for a free sample of the report “Competitive Landscape of Top 50 Contract Research Organizations (CROs),” compiled and published by Grand View Research.

Top 50 CROs' Competitive Landscape Report Coverage

Top 50 CROs Analyzed For
Overview/Historic Development of Company	Key Service Catalog	Talent Pool Strength & Composition
Stages of R&D Covered/Research Expertise	Industry Recognitions/Certifications	Financial Reporting

Get more insights from our in-depth market intelligence report “Healthcare Contract Research Organization Market Size, Share & Trends Analysis Report By Type (Drug Discovery, Pre-clinical, Clinical), By Service (Clinical Monitoring, Data Management), By End-use, By Region, And Segment Forecasts, 2022 – 2030”

About Us

Grand View Research, Inc. is a market research and consulting company that provides off-the-shelf, customized research reports and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and energy. With a deep-seated understanding of varied business environments, Grand View Research provides strategic objective insights.

Find More information @ https://www.grandviewresearch.com/info/trend-reports

Why ESG Matters for Investors in the Electric Scooter Industry

Electric scooters have witnessed a notable journey from risky tech novelty to a green travel solution. The development of more sustainable, safe, affordable, convenient and efficient urban transportation solutions will see consumers transitioning to e-scooters. Electric mobility has witnessed profound traction to encourage environmentally friendly companies to invest in ESG initiatives. An increased commitment to a cleaner planet, sound corporate governance, safety & resilience and social impact will steer EV adoption.

Consumers, think tanks, independent researchers and media have furthered their focus on lightweight electric bikes that can propel carbon neutrality. With air quality, noise and pollution emerging as global concerns, stakeholders could vouch for electric scooters. There are tailwinds galore: accessibility to mobility, convenience and lower environmental impact if decarbonized or renewable energy is used.

Amidst the sustainable aspects of EVs, e-scooter manufacturers have received flak for greenhouse gas emissions during the manufacturing process, moving and managing them. According to a 2019 study from researchers at North Carolina University, e-scooters emit more GHG emissions per mile than traveling by bus, moped, bicycle or on foot. As such, increasing e-scooters' lifespan could be the way forward. Furthermore, e-bikes can be an invaluable addition to commuters to enhance a shared model, and for manufacturers to foster recyclability, improve quality of life and bolster safety.

Key Companies in this theme

    • Hero Electric

    • Yadea Technology Group Co., Ltd.

    • Gogoro Inc.

    • Vmoto Limited

    • BMW Motorrad International

Environmental Perspective

Lately, battery-swapping technology has gained ground to refuel e-scooters and contribute to a sustainable environment. Industry leaders assert that using swappable batteries could help minimize emissions. To illustrate, in February 2023, Gogoro Inc. launched its Impact Report illustrating how battery swapping has become paramount for sustainable transportation. The swapping system can integrate renewable power into electricity grids with demand response and virtual power programs. It has introduced Swap & Go, which offers up to 67% lower GHG emission per passenger kilometer. Besides, in 2022, the Taiwanese company started purchasing renewable energy to further minimize the amount of scope 2 emissions caused by retail operations, manufacturing and battery swapping services. Concrete plans to foster renewable energy, quality maintenance & repairs can underpin sustainable strategies.

Social Perspective

Stakeholders have prioritized e-bikes to offset noise pollution, efficiently use space & preserve public space, safety and foster diversity. According to the European Environment Agency (EEA), over 100 million people are exposed to harmful levels in the EEA-33 member countries, with road traffic becoming infamous as the most prevalent source of environmental noise. Moreover, noise pollution is associated with increased depression, stress and impaired learning abilities. Leaders are expected to promote silent electric mobility to negate noise pollution. Predominantly, diversity has become pivotal to propelling the social profile. According to the VOI ESG Sustainability Statement 2019-2020, 50 nationalities represent its 500 employees from diverse profiles and skill sets. The mobility company has also introduced incentivized parking zones to foster responsible parking. These trends indicate the global electric scooters industry is poised to gain ground as companies strive to unlock the social benefits of EVs.

Is your business one of the participants in the Electric Scooters Industry? Contact us for focused consultation around ESG Investing, and help you build sustainable business practices

Governance Perspective

Unlocking the compelling impact of e-scooters will need transparency, good corporate behavior, ethics & compliance, transparency and board diversity. At a time when sustainable development has become a benchmark to measure a company's value and success, industry players have ramped up efforts to introduce ESG policies. For instance, in October 2021, Yadea formed an ESG Committee to foster green transformation and modern governance. It has also exhibited concerted efforts toward the disclosure of ESG policies. The company is counting on regular reporting to update the public and investors on green initiatives. The Shanghai-based company is well-positioned to foster diversity and maintain a high standard of corporate governance. Yadea has eight directors, including four independent non-executive directors and one non-executive director, according to its Annual Report 2021.

Investors, entrepreneurs and other stakeholders expect bullish policies, consumer acceptance, technology advancements in battery technology, increased lifespan of scooters, renewable energy and improvement in the charging infrastructure to fuel the adoption of two- and three-wheel EVs. In doing so, leading players will bolster their ESG goals and focus on micromobility. To illustrate, Halfords suggests it collected and recycled 4,562kg of used domestic batteries in the U.K. stores in FY 2020. With the recycling efforts becoming pronounced, the marketplace is slated to witness investment galore. The electric scooters market is expected to witness a robust CAGR of 7.8% from 2022 to 2030.

About Astra – ESG Solutions by Grand View Research

Astra is the Environmental, Social, and Governance (ESG) arm of Grand View Research Inc. - a global market research publishing & management consulting firm.

Astra offers comprehensive ESG thematic assessment & scores across diverse impact & socially responsible investment topics, including both public and private companies along with intuitive dashboards. Our ESG solutions are powered by robust fundamental & alternative information. Astra specializes in consulting services that equip corporates and the investment community with the in-depth ESG research and actionable insight they need to support their bottom lines and their values. We have supported our clients across diverse ESG consulting projects & advisory services, including climate strategies & assessment, ESG benchmarking, stakeholder engagement programs, active ownership, developing ESG investment strategies, ESG data services, build corporate sustainability reports. Astra team includes a pool of industry experts and ESG enthusiasts who possess extensive end-end ESG research and consulting experience at a global level.

For more ESG Thematic reports, please visit Astra ESG Solutions, powered by Grand View Research

Legal Cannabis—a Bird’s Eye View on the Regulatory Scenario Based on Countries

The prevalence and acceptance of Cannabidiol (CBD) have encouraged forward-looking companies to shift their attention toward cannabis-based products. The legalization of cannabis for medical purposes will spur market growth. The Thailand government reportedly decriminalized the cultivation, distribution, consumption and marketing of all parts of the cannabis plant by June 2022. A robust regulatory framework will augur innovation and development for incumbent players. Notably, the legalization of cannabis in dozens of U.S. states and Canada has marked a new era in the governments’ approaches to cannabis. 

An in-depth assessment of the regulatory framework from Grand View Research will emphasize cannabis consumption & adoption, trade opportunities, market entry strategies and competitive scenarios of more than 15 countries. The final report, along with the database, will deep-dive on the following industry dynamics:

• Legalization scenario across the U.S. and Europe, ease of doing business and import-export scenario.
• Reintroduction of the MORE Act (Marijuana Opportunity, Reinvestment, and Expungement) in the U.S.
• Insights on clinical trials and studies. 
• Market penetration of established and emerging countries.
• Industry Developments across major regions. 

Get your copy or request for a free sample of the report “Legal Cannabis Regulatory Scenario,” compiled and published by Grand View Research

Legal Cannabis Regulatory Scenario Report Scope

Attributes	Details
Areas of Research	Industry regulatory frameworks, market opportunity, ease of doing business across countries
Report Representation	Consolidated report in PDF format
Country Coverage	15+ Countries
Highlights of Report (Regulatory Framework, by country)	Cannabis Cultivation Norms Import-Export scenario Ease of cannabis business Competitive Landscape Regulatory bodies involved Market Penetration Licensing scenario

Get more insights from our in-depth market intelligence report “Legal Cannabis Market Size, Share & Trends Analysis Report By Source (Marijuana, Hemp), By Derivative (CBD, THC), By End Use (Medical Use, Recreational Use, Industrial Use), By Region, And Segment Forecasts, 2023 – 2030”

About Us

Grand View Research, Inc. is a market research and consulting company that provides off-the-shelf, customized research reports and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and energy. With a deep-seated understanding of varied business environments, Grand View Research provides strategic objective insights.

Find More information @ https://www.grandviewresearch.com/info/trend-reports

ESG Investing in the Air Conditioning Systems Industry

Industry leaders are embracing ESG and investing in diversity, governance and social contribution to foster air conditioning systems. Stakeholders are designing air conditions to make air clean, build a healthy workplace, boost environmental protection, implement measures for climate change and contribute to local communities. Burgeoning urbanization, thriving living standards and scorching heat have fuelled the demand for AC units, spurring the need for ESG rankings and goals.

The onslaught of the COVID-19 outbreak expedited the need for air purification and ventilation, encouraging companies to step up their efforts toward decarbonization. Companies are banking on social missions to curb global warming and offer a reliable and safe air environment. Moreover, the global push for net-zero energy buildings has encouraged stakeholders to invest in ESG metrics.

It is worth mentioning that air conditioners consume more electricity than other home appliances. Demand for air conditioners will continue to gain uptick with soaring temperatures and prevalent heatwaves. According to the IEA, the global demand for space cooling will witness a three-fold rise by 2050. ESG will witness profound traction to negate the effects of scorching heat and propel the penetration of environmentally friendly ACs.

Key Companies in this theme

    • Daikin Industries, Ltd.

    • Mitsubishi Electric Trane HVAC US LLC

    • Hitachi Ltd

    • Carrier

    • Whirlpool Corporation

    • Haier Group

Environmental Perspective

Amidst a surge in demand for AC, stockholders, shareholders and other stakeholders are gearing up to minimize the amount of energy consumption and GHG emissions. Blue Frontier, a sustainable air conditioning technology provider, suggests that AC contributes 5% of global greenhouse gas emissions. Leading players have furthered their inclination toward carbon neutrality to achieve business growth that complements environmental performance. To illustrate, Daikin has formed a "Challenge to achieve carbon neutrality" theme; and has upped efforts to attain net zero greenhouse gas emissions by 2050 (in line with the Environmental Vision 2050). The company claims to have cut net emissions by 10% through the sale of energy efficient products. The Japanese company is contemplating exploring AI and IoT to provide healthy, safe air environments. Developing a roadmap to reducing GHG emissions and similar bullish targets will bolster the brand position in the global landscape.

Social Perspective

Brands have emphasized employee well-being, health & safety and diversity, equity and inclusion (DEI) to unlock sustainable growth potentials. Notably, Hitachi aims for a 30% ratio for female and non-Japanese Executive and corporate officers by 2030. It has formed DEI promotion leaders in each region to expedite diversity. Companies are expected to undergird training programs to enhance individual skills, capabilities and specialties. Moreover, the spotlight on work-life management has become pronounced following the gray areas uncovered by the COVID-19 pandemic across business verticals. Hitachi is doing away with overwork and long working hours, fostering nursing- and child care. It has also strengthened health & safety measures by conducting occupational health & safety risk assessments. Besides, around 40.3% of employees have received special health guidance, alluding to a buoyant initiative to boost employee health.

Is your business one of the participants in the Air Conditioning Systems Industry? Contact us for focused consultation around ESG Investing, and help you build sustainable business practices

Governance Perspective

The trend for sustainable business growth with fairness, honor, corporate behavior, sound corporate governance, ethics & compliance and transparency has become indispensable. Well-established players have furthered their emphasis on board diversity as it reflects differences in professional experiences, viewpoints, skills, educational backgrounds, national origin, race, gender and age. In essence, 12 out of 13 directors at Whirlpool are independent and each of the board's four committees comprises independent directors. Prominently, 33% of the independent directors are women, while 25% belong to ethnic/racial minorities. In 2021, the Board, with external advisors, partook in an education session on ESG trends. It is worth noting that the committees of the Board oversee the facets of ESG risk monitoring and implementation.

The competitive landscape indicates an increased emphasis on organic and inorganic strategies to gain a stronghold in the competitive environment. Industry leaders are expected to fulfill their responsibilities toward society, planet and foster corporate value with an investment in a sustainable supply chain. To illustrate, in July 2022, Blue Frontier announced an infusion of USD 20 million in Series A funding to underpin the goal of eradicating billions of tons of GHG emissions. With cooling poised to overtake heating demand, companies are likely to introduce AC that is sustainable, efficient and affordable, along with reduced energy storage cost. The global air conditioning systems market could observe around 6.2% CAGR between 2021 and 2028.

About Astra – ESG Solutions by Grand View Research

Astra is the Environmental, Social, and Governance (ESG) arm of Grand View Research Inc. - a global market research publishing & management consulting firm.

Astra offers comprehensive ESG thematic assessment & scores across diverse impact & socially responsible investment topics, including both public and private companies along with intuitive dashboards. Our ESG solutions are powered by robust fundamental & alternative information. Astra specializes in consulting services that equip corporates and the investment community with the in-depth ESG research and actionable insight they need to support their bottom lines and their values. We have supported our clients across diverse ESG consulting projects & advisory services, including climate strategies & assessment, ESG benchmarking, stakeholder engagement programs, active ownership, developing ESG investment strategies, ESG data services, build corporate sustainability reports. Astra team includes a pool of industry experts and ESG enthusiasts who possess extensive end-end ESG research and consulting experience at a global level.

For more ESG Thematic reports, please visit Astra ESG Solutions, powered by Grand View Research

U.S. Ophthalmic Devices—a Deep-dive on the Patient Population based on Gender and Age Groups

The burgeoning aging population and a surge in obesity & diabetic cases have put the spotlight on advanced ophthalmic devices. The National Institute on Aging (NIA) estimates the geriatric population to reach 72 million by 2030, while the WHO suggests around 422 million people are living with diabetes. These trends imply the prevalence of vision impairment and blindness due to diabetic retinopathy, cataracts, glaucoma, age-related macular degeneration and vitreo-retinal disorders. Besides, the onset of the COVID-19 outbreak led to increased screen time, spurring the demand for eye examinations. 

Grand View Research has aptly paid heed to the evolving customer preferences and the paradigm shift witnessed in the healthcare & medical space. The final report, along with the database, will deliberate upon the following industry dynamics:

• The demand for minimally invasive surgeries, including multi-wavelength diabetic retinopathy treatment and LASIK surgery.
• Trend for ophthalmic devices across hospitals and eye clinics. 
• Early detection and treatment of eye diseases to help prevent vision loss. 
• Significance of adults receiving eye exams: The American Academy of Ophthalmology mentions that over 22 million adults grapple with vision impairment, and 61 million U.S. adults are at a high risk of vision loss. 
• The influence of AI as well as the impact of campaigns and programs.

Get your copy or request for a free sample of the report “U.S. Ophthalmic Patient Population Statistics Study Report”, compiled and published by Grand View Research.

Attribute	Details
U.S. Ophthalmic Patient Population (2022)	Age Groups Gender Glass Vs Contact Lenses Single Vision Vs Multifocal Number of LASIK surgeries Ethnicity Population wearing glasses % of people that wear glasses for Single Vision Vs Multifocal Number of people wearing bifocal, trifocal, and progressive lenses % of the population that has an oculus dexter and oculus sinister measurement between -6 and +6 in the prescription)

Get more insights from our in-depth market intelligence report “Ophthalmic Devices Market Analysis By Product (Optical Coherence Tomography, Ophthalmic Ultrasound), By Application (Cataract, Glaucoma), By End Use (Hospitals and Eye Clinics) And Segment Forecasts, 2022 – 2030.”

About Us
Grand View Research, Inc. is a market research and consulting company that provides off-the-shelf, customized research reports and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and energy. With a deep-seated understanding of varied business environments, Grand View Research provides strategic objective insights.

Find More information @ https://www.grandviewresearch.com/info/trend-reports

ESG in the Footwear Industry: A Comprehensive Overview

Shoe companies have witnessed C-suite leaders prioritize sustainability, a shift in company cultures showing the footwear industry making giant strides beyond corporate promises. Stakeholders are developing KPIs and bullish strategies to foster ESG reporting. Although the COVID-19 pandemic has had a compelling impact on industries, 2023 through 2030 should see more companies start to report sustainability both to the public and internally.

With millions of footwear inundating landfills, manufacturing of environmentally preferred materials (EPMs) has become pronounced. Sustainable use of resources, including water, energy and materials, has become the next big thing. Prominently, Adidas is contemplating replacing virgin polyester with recycled polyester by 2024. The footwear giant is bullish that 9 out of its 10 articles will have a sustainable material by 2025. Moreover, in 2021, the sportswear company aimed to use recycled marine plastic waste to manufacture 17 million pairs of shoes. During the period, Tier 1 suppliers attained a 15% dip in water intensity, while Tier 2 suppliers observed an 18% plunge.

Forward-looking companies are zeroing in on augmenting the adoption of renewable energy and boosting energy efficiency. Gen Z and millennials are expected to seek products made from materials that can be recycled, reused or repurposed. Besides, socially compliant and sound corporate governance-focused companies will remain ahead of the curve in a competitive footwear industry.

Key Companies

    • Nike, Inc.

    • Adidas AG

    • PUMA

    • Geox S.p.A

    • Timberland

    • Skechers U.S.A, Inc

    • Crocs Retail, LLC

Environmental Perspective

Contract manufacturers, material vendors and shoe companies have upped their environmental strategies to tap into the potential opportunities and enhance their ESG profiles. In essence, Caleres Inc. is vying to recycle, reclaim, or refurbish 90,000 pairs of shoes each year. The American footwear brand mentioned in its inaugural ESG report that environmentally preferred materials will be used for 25% of footwear sold in Famous Footwear. Moreover, the EPM will also be used in 100% of Caleres products and shoeboxes by 2025. Footwear material solution providers have furthered their emphasis on recycled materials, bio-based materials, waterless dying, material consolidation and waste reduction to propel their shoe sustainability profiles.  

Social Perspective

Lately, incorporating diversity, equity and inclusion (DEI) has become the talk of the town as leading players strive to create a positive change in the industry, protect the rights of employees and leverage a culture of acceptance and belonging. To illustrate, Nike had a 50.4% representation of women in the global corporate workforce during FY 2021. NIKE Impact Report notes that the American multinational company has 100% pay equity across all employee levels on an annual basis and offers equitable and competitive benefits for all employees. It also fostered relationships with more than 50 external partners, such as Lesbians Who Tech, the Mom Project and Women Who Code, enabling the footwear behemoth to hire candidates from various backgrounds. Considering the soaring demand for socially sustainable footwear, leading shoe brands are poised to emphasize ESG pillars.

Is your business one of the participants in the Footwear Industry? Contact us for focused consultation around ESG Investing, and help you build sustainable business practices

Governance Perspective

The significance of sound corporate governance has gained new heights to oversee sustainability initiatives, DEI opportunities, community affairs and labor practices. In essence, at Puma, leaders from CEO to the Team Head level have clearly defined sustainability targets in line with its Forever Better Sustainability Strategy. It is worth noting that the strategy is based on 10FOR25 target areas, including Human Rights, Climate Action, Plastic and the Oceans and Circularity, to integrate sustainability into the core business functions.

The German sporting goods company has underscored gender balance at management levels and reinforced the ratio of women in leadership positions. As of November 2022, women have filled 44% of leadership positions at Puma. Further, employees in leadership positions are trained in intercultural communication, diversity and inclusion, exhibiting commitment to a tolerant and open work environment through buoyant governance.

The effective implementation of ESG practices, along with organic and inorganic growth strategies, has become paramount to adding value to the company's growth. To put this in perspective, footwear companies are poised to use sustainability to systematically address challenges focusing on technological advancements, geographical expansion, ESG reporting and bullish sustainability targets. For instance, by May 2021, On met its goal to use 100% recycled, FSC-certified cardboard, as well as 100% recycled HDPE in its apparel packaging, the Zurich-based athletic company stated in the Impact Progress Report 2021.

Given the social and political pressure shoe companies grapple with, industry leaders are expected to act proactively to stay ahead of the game. According to Grand View Research, the global footwear market size stood at USD 373.19 billion in 2021 and could depict a 4.3% CAGR between 2022 and 2030.

About Astra – ESG Solutions by Grand View Research

Astra is the Environmental, Social, and Governance (ESG) arm of Grand View Research Inc. - a global market research publishing & management consulting firm.

Astra offers comprehensive ESG thematic assessment & scores across diverse impact & socially responsible investment topics, including both public and private companies along with intuitive dashboards. Our ESG solutions are powered by robust fundamental & alternative information. Astra specializes in consulting services that equip corporates and the investment community with the in-depth ESG research and actionable insight they need to support their bottom lines and their values. We have supported our clients across diverse ESG consulting projects & advisory services, including climate strategies & assessment, ESG benchmarking, stakeholder engagement programs, active ownership, developing ESG investment strategies, ESG data services, build corporate sustainability reports. Astra team includes a pool of industry experts and ESG enthusiasts who possess extensive end-end ESG research and consulting experience at a global level.

For more ESG Thematic reports, please visit Astra ESG Solutions, powered by Grand View Research